Succinic acid
Succinic acid
110-15-6
disodium succinate
Phthalocyanine pigment
Compound dyes
Compound green
Composite blue
Succinic acid(cas:110-15-6) adsorption from fermentation broth and regeneration
Release time:2016/7/14 14:06:11

More than 25 sorbents were tested for uptake of succinic acid from aqueous solutions. The best resins were then tested for successive loading and regeneration using hotwater. The key desired properties for an ideal sorbent are high capacity, complete stable regenerability, and specificity for the product. The best resins have a stable capacity of about 0.06 g of succinic acid/g of resin at moderate concentrations (1-5 g/L) of succinic acid(cas:110-15-6). Several sorbents were tested more exhaustively for uptake of succinic acid(cas:110-15-6) and for successive loading and regeneration using hot water. One resin, XUS 40285, has a good stable isotherm capacity, prefers succinate over glucose, and has good capacities at both acidic and neutral pH. Succinic acid was removed from simulated media containing salts, succinic acid, acetic acid, and sugar using a packed column of sorbent resin, XUS 40285. The fermentation byproduct, acetate, was completely separated from succinate.


A simple hot water regeneration successfully concentrated succinate from 10 g/L (inlet) to 40--110 g/L in the effluent. If successful, this would lower separation costs by reducing the need for chemicals for the initial purification step. Despie promising initial results of good capacity (0.06 g of succinic/g of sorbent), 70% recovery using hot water, and a recovered concentration of >100 g/L, this regeneration was not stable over 10 cycles in the column. Alternative regeneration schemes using acid and base were examined. Two (XUS 40285 and XFS-40422) showed both good stable capacities for succinic acid over 10 cycles and >95% recovery in a batch operation using a modified extraction procedure combining acid and hot water washes. These resins showed comparable results with actual broth.


Over twenty four adsorbents have been tested for uptake of succinic acid(cas:110-15-6) (SA) from aqueous solutions. The best resins were then tested for successive loading and regeneration using hot water. The key desired properties for an ideal adsorbent are high capacity, complete stable regenerability, and specificity for the product. The best resins have a stable capacity of -0.06 g succinic acid/g resin at moderate concentrations of SA. Several sorbents were tested more exhaustively for uptake of succinic acid(cas:110-15-6) and for successive loading and regeneration using hot water. One resin, XUS 40285, has a good stable isotherm capacity, prefers succinate over glucose, and has good capacities at both acidic and neutral pH. succinic acid(cas:110-15-6) was removed from simulated media containing salts, succinic acid, acetic acid, and sugar using a packed column of adsorbent resin, XUS 40285.


The fermentation byproduct, acetate, was completely separated from succinate. A simple hot water regeneration successfully concentrated succinate from 10 g/L (inlet) to 40-110 g/L in the effluent. If successful, this would lower separation costs by reducing the need for chemicals for the initial purification step. Despite promising initial results of good capacity (0.06 g succinic/g sorbent), 70% recovery using hot water, and a recovered concentration of >100 g/L, this regeneration was not stable over ten cycles in the column. Alternative regeneration schemes using acid and base were examined and more sorbent screened. Tests were performed with both simulated broth containing succinic acid(cas:110-15-6) at various concentrations and with actual broth provided by MBI. Seven of the most promising resins were tested for regenerability and stability using a modified extraction procedure combining acid and hot water washes. Two (XUS 40285 and XFS) showed both good stable capacities for succinic acid over ten cycles and more than 95% recovery in a batch operation. These results indicate that sorption for succinic acid(cas:110-15-6) continues to be promising. However, it will need additional column and process tests focusing on the regeneration of the resins and the concentration of the succinic acid in the effluent streams



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