Succinic Acid CAS# 110-15-6 quality assurance price
Succinic Acid CAS 110-15-6 manufacturer spot Succinic acid, Succinic acid
quality assurance price
Succinic acid is an important "C4 platform compound", which is widely used
in food, medicine and agriculture, as a raw material for the synthesis of
1,4-butanediol, tetrahydrofuran, N-methylpyrrolidone and biodegradable
biopolymers such as polybutylene glycol succinate. The biosynthesis of 1 molar
butanedioic acid will be a promising application. The biosynthesis of 1 mole of
succinic acid will fix 1 mole of carbon dioxide, so the production of succinic
acid by fermentation with carbon dioxide as raw material can not only reduce the
cost of raw materials, but also reduce greenhouse gas emissions.
Succinic acid is also known as succinic acid. The molecular formula
HOOCCH2CH2COOH. Succinic acid is found in amber, but also in a wide variety of
plants and human and animal succinic acid tissues, such as immature grapes,
beets and rhubarb, human blood and muscle, bovine brain, spleen and thyroid
gland. Succinic acid is an intermediate in the metabolism of carbohydrates in
the body. Succinic acid is widely distributed in the animal and plant kingdoms
and was first discovered in 1550 by Agricola during the distillation of amber,
hence the name succinic acid. Succinic acid (SA) is an intermediate in the
synthesis of many organic substances and an important raw material for the
manufacture of drugs, and is widely used in food, medicine and chemical
industry. It is widely used in food, medicine, chemical industry and other
fields, and with the development of the times, there are new breakthroughs in
the application of succinic acid and its extension products.
Succinic acid is colorless crystal; relative density 1.572(25/4℃), melting
point 188℃, decompose at 235℃; can be sublimated by distillation under reduced
pressure; soluble in water, slightly soluble in ethanol, ether and acetone. As
ionic chelating agent, succinic acid is used in the electroplating industry to
prevent dissolution and pitting of metals; Succinic acid is a good surfactant, a
component of descaling agents, soaps and emulsion breakers; Succinic acid can
produce depilatory agents, toothpaste, cleaning agents, efficient wrinkle beauty
esters. Succinic acid is also used in lubricants, additives, and elastomers.
Basic information
Chinese name: succinic acid
English name: succinic acid
Chinese name 2: succinic acid
English name 2: amber acid
CAS No.: 110-15-6
Molecular formula: C4H6O4
Molecular weight: 118.09
Physical and chemical properties
Main components: Content: ≥99.0%; sulfate ≤0.02%; heavy metal ≤0.002%; iron
≤ 0.002%; ash ≤ 0.1%.
Appearance and properties: Colorless or white, odorless and acidic
prismatic or flaky crystals.
Melting point(℃): 185
Boiling point(℃): 235(decomposition)
Relative density (water=1): 1.57(15℃)
Solubility: soluble in water, ethanol, ether, acetone.
Succinic acid is widely used in pharmaceutical, dye, paper, textile, spice,
coating, food, plastic and other industries; currently, the sales volume of
industrial grade succinic acid is over 15,000t, largely produced by
petrochemical method from butane through cis-butenedianhydride. Only succinic
acid for the food market is produced by the fermentation method.
Butanedioic acid produced from butanedioic acid alkyd resin has good
flexibilization, elasticity and water resistance, which can be used in the
pharmaceutical industry to produce sulfonamides, vitamin A, vitamin B and
hemostatic drugs; diphenyl ester of butanedioic acid is an intermediate of
dyestuff, and reacts with amino anthraquinone to produce anthraquinone dyestuff;
in addition, butanedioic acid also has a wide range of uses in paper
manufacturing, textile industry, and can also be used as lubricants,
photographic chemicals and It is also used as a raw material for lubricants,
photographic chemicals and surfactants. Succinic acid is also used as a food
acidifier for flavoring wine, feed, and candy. With sales of more than $400
million per year, it is conceivable that the market for succinic acid is quite
large, so the main markets for succinic acid are in the following areas.
? Food industry application areas
Directly applied in food.
1、Acid (chemical) agent ;
2、Buffering agent, neutralizing agent;
3、Japanese sake, fermented soybean paste, soy sauce, cool drinks, sugar
products and other flavoring agents.
Synthesize a variety of food additives from other raw materials.
1, emulsifier, dough improver, nutritional supplements;
2、Preparation of berry flavors and as a solvent for fruit-based spices;
3, flavor improver, acidifier, mainly used in the preparation of soy sauce
and used in sausage, ham, surimi products, etc;
4、Dried shellac.
? Chemical industry applications
1、Biodegradable plastic (PBS);
2、Dimethyl succinate;
3、Electroplating PH value adjusting agent;
4、Alkyd resin;
5、Dyestuff;
6、Varnish viscosity stabilizer;
7、Lubricants and surfactants for photographic chemicals;
8、Candles.
? Pharmaceutical industry applications
1、Diuretics, expectorants, vitamin A, vitamin B, sulfonamides, synthesis of
hemostatic drugs;
2、Antidote, antitussive agent;
? Other application areas
1、An important organic reagent;
2、A widely used plant growth hormone.
Preparation method
Used in the preparation of pentacyclic compounds. The product is an organic
chemical raw material with a wide range of applications. Dosing -
electrochemical synthesis - decolorization - cooling crystallization - static
system - centrifugal separation - drying - packaging
There are more industrial preparation methods, mainly as follows.
1. Oxidation method
Paraffin wax is deeply oxidized to produce a mixture of various carboxylic
acids, and then separated by water distillation and crystallization to obtain
succinic acid.
2. Hydrogenation method
Hydrogenation of maleic anhydride or transbutenedioic acid under the action
of a catalyst produces succinic acid, which is then separated to obtain the
finished product. The catalyst is nickel or precious metal, and the reaction
temperature is about 130- 140℃.
3. Acrylic acid carbonyl synthesis method
Acrylic acid and carbon monoxide in the presence of a catalyst to produce
butanedioic acid. Not yet industrialized.
4. Electrolytic oxidation method
Phthalic anhydride and sulfuric acid and water in the ratio of 1:0.5:4,
electrolysis in a ceramic electrolyzer, can be obtained butanedioic acid.
Electrolytic synthesis of raw materials for maleic acid or maleic anhydride,
cathode and anode solution with dilute sulfuric acid, separated by a cationic
membrane, cathode and anode are generally used lead plate, usually with a plate
and frame electrolyzer synthesis.
5. Acetylene method
Acetylene reacts with carbon monoxide and water in the presence of
[CO(CO)4] catalyst in acidic medium to obtain succinic acid, reaction
temperature 80-250℃, pressure 2.94-49.03MPa.
6. Emerging fermentation method
Compared with traditional chemical methods, microbial fermentation method
for succinic acid production has many advantages: competitive production cost;
use of renewable agricultural resources, including carbon dioxide, as raw
materials, avoiding the dependence on petrochemical raw materials; reduce the
pollution of the environment by chemical synthesis process.
Precautions: Less toxic, irritating to eyes, skin and mucous membranes, not
toxic to the whole body. This product is flammable and irritating. Less toxic,
irritating to eyes, skin and mucous membranes, but not toxic to the whole
body.
Environmental hazards: It is hazardous to the environment and can cause
pollution to water bodies and the atmosphere.
Flammability hazard: The product is flammable and irritating.
Hazardous characteristics: Flammable when exposed to open flame and high
heat. Powder and air can form an explosive mixture, when it reaches a certain
concentration, it will explode in contact with a spark. Decomposition by high
heat, emitting irritating fumes.
Pharmacological effects
1. Antibacterial effect of succinic acid at a concentration of 2mg/ml has
an inhibitory effect on Staphylococcus aureus, Staphylococcus catarrhalis and
Bacillus typhi, Pseudomonas aeruginosa, S. dysenteriae.
2. Central inhibitory effect rats, mice, guinea pigs, rabbits, cats and
dogs intraperitoneal injection of succinic acid can protect animals against
hyperbaric, electroconvulsive and auditory convulsions. The anticonvulsant
effect is associated with increased GABA content in the brain. Hot plate method
has analgesic effect and synergistic effect with pentobarbital, as well as
sedative and hypothermic effect.
3. Anti-ulcer effect on gastric ulcer produced by pyloric ligation in rats,
50mg/kg injected intraperitoneally or orally, anti-ulcer effect due to
inhibition of gastric juice secretion and dilatation of gastric muscle.
4. Effects on immune function: Succinic acid was dissolved in saline and pH
adjusted to 6.4 by adding NaHCO3 at a concentration of 11.8%. 1mM (118mg)/kg,
2.5mM (295mg)/kg and 5mM (590mg)/kg were injected intraperitoneally into rats
and rabbits daily for 7d, once daily. 0.025), but the increase in phagocytosis
was not significant. In rabbits, the leukocyte count increased significantly at
higher doses, and the phagocytosis rate also increased (P<0.01). In the specific skin reaction test, intraperitoneal injection of succinic acid 5mg/kg for 4 times in 48h or once daily for two weeks, succinic acid inhibited passive and active skin allergic reactions in rabbits and reduced the formation of serum 1gE antibody in animals.
5.Antitoxic effect Succinic acid has obvious protective effect on mice in
poisonous cobra, and the rate of protection is similar to the original
formula.
Source of ingredients
Succinic acid natural source is the resin of the pine plant buried in the
ground for a long time to become amber, etc., in addition to a wide range of
plants, animal tissue. Succinic acid is the resin of pine plant, buried in the
ground for a long time to make amber, amber contains 7.8% of this product.
Angelica sinensis (Oliv.) Diels root of Umbelliferae, Pothos chinensis (Raf.)
Merr. of Tennantaceae, Lesspedeza caneata G. Don of Leguminosae, Lo-belia
chinen-sis of Erythrinaceae Lour. whole herb, Orchidaceae Sarcardra glabra
(Thumb.) Nakai whole herb, Sandalwood spice plant Thesium chinense Turcz. whole
herb. Leguminosae Cloverleaf; Umbelliferae Angelicae Root; Tennantaceae Vine
Orange; Erythrinaceae Hemipterocarpus; Orchidaceae; Sandalwood and Strawberry.
Grapes, etc.
Product Center
Succinic acid (succinic acid) series
Succinic acid, disodium succinate(hexahydrate), disodium
succinate(anhydrous), dipotassium succinate, calcium succinate, ammonium
succinate, dimethyl succinate, diethyl succinate, diisopropyl succinate;
Phthalocyanine pigment series
Phthalocyanine blue BGS 15:3, Phthalocyanine blue BGS 15:4, Phthalocyanine
blue B 15, Phthalocyanine green G 7, Copper phthalocyanine intermediate ≥95%
Product advantages
As the industry benchmark of supply chain service in the field of chemical
products, we have senior industry experience and provide market advantageous
price, and have won excellent reputation among many customers.
Industry field Strong strength
As the industry standard of supply chain service in the field of chemical
products, we have perfected a set of accurate operation system and established
long-term stable and reliable cooperation relationship with many famous chemical
companies and large refineries.
Full range of products and sufficient inventory
The company currently operates more than a thousand kinds of chemical
products, with factories, barrels, bagged warehouses, liquid storage tanks
around the world; large storage capacity, stable supply
Professional team Service on paper
We have rich international trade experience and professional talents in the
chemical field, professional customer service team "one-to-one" refinement
service, to provide accurate quotation and consulting services, for your
procurement comprehensive gate-keeping.
High quality products High quality price
Focus on the process of product quality control, adhere to only "genuine";
senior industry experience, to provide market advantageous prices, and won a
good reputation among many customers.
About US
Anhui San-Xin Chemical Co., Ltd. is a manufacturer and operator of fine
chemicals, including succinic acid, succinic anhydride and their derivatives.
Our products include: succinic acid, succinic anhydride, sodium succinate,
potassium succinate, butanediimide, dimethyl succinate, diethyl succinate,
dibutyl succinate, etc. Our products are sold nationwide and overseas. Its
products are sold nationwide and overseas and are widely used in
pharmaceuticals, pesticides, dyestuffs, synthetic spices, synthetic resins,
plastic additives, food additives, chemical analysis, electroplating and other
fields.
The products are widely used and more than 90% of them are exported to more
than 20 countries and regions such as USA, UK, Japan, France, Germany,
Australia, Middle East, Hong Kong, Taiwan, Macau, etc. The sales network of the
products spreads all over China and we have established long-term business
relationships with some large and medium-sized enterprises. In 1997, it was
recognized as a provincial high-tech product.
Our main products include food preservatives, food flavors and fragrances,
food sweeteners, food emulsifiers, food bulking agents, food thickeners,
antioxidants, nutritional fortificants, amino acids, vitamins, health care raw
materials, pharmaceutical excipients and other products. The company has strict
quality control procedures, scientific business management and efficient
logistics operation system, which provide a solid guarantee for the customers to
get stable, safe and high quality food additives. We strictly implement the
requirements of ISO9001:2008 quality management system standard, and on the
basis of this, our succinic acid series products have passed STAR-K
certification, FDA certification, etc. Our main production and operation
products are: succinic acid series products; we also deal with phthalocyanine
organic pigment series, iron oxide series, refined anhydrous calcium chloride
and other products.
The essence of Qino's corporate culture is "scientific and open, innovative
and enterprising, behave honestly and do real work", which is interpreted with
different cultural connotation at different times, and will inspire our Qino
staff to strive for the pursuit. In today's increasingly competitive market, we
will take strict product quality, reasonable transaction price, after-sales
service and honest business reputation as the basis, in accordance with the
company values of "the best and the most beautiful, mutual benefit and win-win",
with a well-qualified, technical, young and competent staff team, in line with "
Customer first, service" business philosophy, and the majority of business
partners sincere cooperation, common development, and create a better future.
For a long time, San-Xin people pursue the corporate philosophy of honesty and
trustworthiness, customer first, and the enterprise spirit of dedication,
collaboration, pragmatism and innovation, so that you can feel the sincere and
satisfactory San-Xin service. Looking ahead, there is a long way to go, we will,
as always, strengthen the friendship and cooperation with friends from all walks
of life at home and abroad to promote the development of our common cause!
The future, butanedioic acid market development prospects
Succinic acid has a wide range of promising applications in food,
pharmaceuticals, surfactants, green solvents, biodegradable plastics and other
fields, and the chemical products market for its derivatives has a large
potential. The most promising market at present is as the main raw material for
the biodegradable plastic polybutylene glycol succinate. At present, the
technology of synthesizing PBS biodegradable plastic from succinic acid has been
successfully developed and put into mass production in BASF, Mitsubishi,
Tsinghua University and Institute of Physical and Chemical Sciences, Chinese
Academy of Sciences, etc. Compared with other biodegradable plastics, PBS not
only has excellent mechanical properties, but also has reasonable price and high
market demand.
In the future, the annual demand of PBS in China will reach more than 3
million tons, based on the production of 1 ton of PBS consuming 0.62 tons of
succinic acid, the consumption of 1.8 million tons of succinic acid, and the
current annual production capacity of succinic acid in China is far from being
able to meet the needs of the market, the market growth of succinic acid is
huge. At present, a number of domestic enterprises are actively preparing to
start PBS projects, has successfully produced PBS enterprises Anqing and Xing
2009 production capacity of 10,000 tons, ready to follow up on the annual
production capacity of 100,000 tons, Xinfu Pharmaceuticals annual production
capacity of 3,000 tons, etc.. And with the successful development of PES plastic
(organic polymer material obtained by condensation of succinic acid and ethylene
glycol) and PHS plastic (organic polymer material obtained by condensation of
succinic acid and adipic acid), two new degradable plastics, the demand for
succinic acid will increase greatly. However, the traditional method of
producing succinic acid which has been using non-renewable strategic resource
petroleum products as raw materials has led to high prices and pollution,
inhibiting the development potential of succinic acid as an excellent chemical
platform product. The foreign production of succinic acid through
biofermentation method uses cheap raw materials, and after reasonable process
optimization, produces succinic acid products with more tremendous advantages
and development potential, and with China's green industry attention, especially
under the growing demand for global sustainable solutions, the competitiveness
of biodegradable bio-based polybutylene succinate is enhanced, which will make
the bio-based butanedioic acid market become bigger and this method will have a
huge development potential.
