Biotechnology of succinic acid production and markets for derived industrial products. Succinic acid(cas:110-15-6), derived from fermentation of agricultural carbohydrates, has a specialty chemical market in industries producing food and pharmaceutical products, surfactants and detergents, green solvents and biodegradable plastics, and ingredients to stimulate animal and plant growth.

As a carbon-intermediate chemical, fermentation-derived succinate has the potential to supply over 2.7?×?108?kg industrial products/year including: 1,4-butanediol, tetrahydrofuran, butyrolactone, adipic acid, n-methylpyrrolidone and linear aliphatic esters. Succinate yields as high as 110?g/l have been achieved from glucose by the newly discovered rumen organism Actinobacillus succinogenes. Succinate fermentation is a novel process because the greenhouse gas CO2 is fixed into succinate during glucose fermentation.

New developments in end-product recovery technology, including water-splitting electrodialysis and liquid/liquid extraction have lowered the cost of succinic acid(cas:110-15-6) production to U.S. $ 0.55/kg at the 75?000 tonne/year level and to $ 0.55/kg at the 75?000 tonne/year level and to 2.20/kg at the 5000 tonne/year level. Research directions aimed at further improving the succinate fermentation economics are discussed.